Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.68 |
| ▸ | HTR6 | P50406 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 6/20 | 0.60 |
| ▸ | HTR2C | P28335 | 5/20 | 0.60 |
| ▸ | HTR2B | P41595 | 5/20 | 0.60 |
| ▸ | HTR1B | P28222 | 4/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR5A | P47898 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30630389 | 1.00 | HTR2A (0.68) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL30630313 | 0.98 | HTR2A (0.71) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL25074497 | 0.98 | HTR2A (0.71) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL30928236 | 0.97 | HTR2A (0.69) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL25790684 | 0.95 | HTR2A (0.73) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL31634311 | 0.94 | HTR2A (0.71) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL30630344 | 0.93 | HTR2A (0.64) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL24168523 | 0.93 | HTR2A (0.64) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL25790565 | 0.93 | HTR2A (0.76) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL25792493 | 0.92 | HTR2A (0.78) | HTR2AHTR6HTR1AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | COMPASS PATHFINDER LIMITED (GB) | 2024-02-08 | — | — | US | disclosed |
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230167141-A1 | PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS | MINDSET PHARMA INC. (CA) | 2023-06-01 | — | — | US | disclosed |
| US-20230167141-A1 | PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS | MINDSET PHARMA INC. (CA) | 2023-06-01 | — | — | US | disclosed |
| US-11591353-B2 | Psilocin derivatives as serotonergic psychedelic agents for the treatment of CNS disorders | MINDSET PHARMA INC. (CA) | 2023-02-28 | — | — | US | disclosed |
| US-20220177427-A1 | Tryptamine Prodrugs | REUNION NEUROSCIENCE CANADA INC. (CA) | 2022-06-09 | — | — | US | disclosed |
| US-11292765-B2 | Tryptamine prodrugs | FIELD TRIP PSYCHEDELICS INC. (CA) | 2022-04-05 | — | — | US | disclosed |
| US-20210403425-A1 | TRYPTAMINE PRODRUGS | REUNION NEUROSCIENCE, INC. | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292765-B2 | Tryptamine prodrugs | HTR2A, HTR5A, HTR2C | HTR2A 1/4885HTR6 13/4885HTR1A 4/4885 |
| US-11591353-B2 | Psilocin derivatives as serotonergic psychedelic agents for the treatment of CNS disorders | HTR1A, HTR6, HTR1B | HTR2A 4/4885HTR6 2/4885HTR1A 1/4885 |
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | INMT, AANAT, HNMT | HTR2A 53/4885HTR6 57/4885HTR1A 181/4885 |
| US-20210403425-A1 | TRYPTAMINE PRODRUGS | HTR2A, HTR5A, HTR2C | HTR2A 1/4885HTR6 13/4885HTR1A 4/4885 |
| US-20220177427-A1 | Tryptamine Prodrugs | HTR2A, HTR5A, HTR2C | HTR2A 1/4885HTR6 13/4885HTR1A 4/4885 |
| US-20230167141-A1 | PSILOCIN DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS | HTR1A, HTR6, HTR1B | HTR2A 4/4885HTR6 2/4885HTR1A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.