Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Hydroxy Quinaldine SCHEMBL2429891 | 0.89 | METAP2 (0.79) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL28154168 | 0.87 | METAP2 (0.82) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL6037117 | 0.87 | METAP2 (0.82) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL8609920 | 0.87 | METAP2 (0.96) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL30295552 | 0.87 | METAP2 (0.96) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL5089361 | 0.87 | METAP2 (0.96) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL262742 | 0.87 | METAP2 (0.96) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL546577 | 0.87 | METAP2 (0.96) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL4304584 | 0.87 | METAP2 (0.96) | METAP2KDM4EPLAUNCF1KMT2A | |
| 8-Hydroxy Quinaldine SCHEMBL2433878 | 0.86 | METAP2 (0.74) | METAP2KDM4EPLAUNCF1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190214575-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE | JNC CORPORATION (JP) | 2019-07-11 | — | — | US | disclosed |
| US-9590182-B2 | Benzofluorene compound, material for luminescent layer using said compound and organic electroluminescent device | JNC CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9478750-B2 | Anthracene derivative and organic electroluminescent element using the same | JNC CORPORATION (JP) | 2016-10-25 | — | — | US | disclosed |
| EP-2897184-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE | JNC Corporation (JP) | 2015-07-22 | — | — | EP | disclosed |
| US-20150097162-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE | JNC CORPORATION (JP) | 2015-04-09 | — | — | US | disclosed |
| US-20140319510-A1 | BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | JNC CORPORATION (JP) | 2014-10-30 | — | — | US | disclosed |
| EP-1935919-B1 | POLYMER CONTAINING SULFO GROUP AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE POLYMER | YAMAMOTO CHEMICALS INC (JP) | 2012-09-05 | — | — | EP | disclosed |
| US-8012608-B2 | Polymer containing sulfo group and organic electroluminescent element containing the polymer | Yamamoto Chemcials, Inc. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20090230851-A1 | Polymer Containing Sulfo Group and Organic Electroluminescent Element Containing the Polymer | MITSUI CHEMICALS, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20080160347-A1 | Benzofluorene compound, emission materials and organic electroluminescent device | JNC CORPORATION (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-1935919-A1 | POLYMER CONTAINING SULFO GROUP AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE POLYMER | Mitsui Chemicals, Inc. (JP) | 2008-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080160347-A1 | Benzofluorene compound, emission materials and organic electroluminescent device | LEF1, TRPA1, BRD8 | METAP2 4227/4885KDM4E 1083/4885PLAU 4499/4885 |
| US-20190214575-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE | L1CAM, VDAC1, VDAC2 | METAP2 2832/4885KDM4E 1253/4885PLAU 1668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.