Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 9/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.46 |
| ▸ | CDK2 | P24941 | 9/20 | 0.46 |
| ▸ | CDK9 | P50750 | 9/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 7/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24352863 | 0.89 | CCNT1 (0.44) | CCNT1CCNA2CDK2CDK9ADRA1D | |
| SCHEMBL28507020 | 0.79 | CCNT1 (0.60) | CCNT1CCNA2CDK2CDK9ADRA1D | |
| SCHEMBL30507485 | 0.79 | CCNT1 (0.60) | CCNT1CCNA2CDK2CDK9ADRA1D | |
| SCHEMBL23330116 | 0.78 | TRPM8 (0.42) | ADRA1DADRA1AADORA2AHSP90AA1ADRA2C | |
| SCHEMBL24352862 | 0.78 | CYP1A2 (0.42) | ADORA2AADRA2C | |
| SCHEMBL24352278 | 0.77 | CASP6 (0.40) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL24352623 | 0.75 | BCHE (0.38) | FEN1ADRA2C | |
| SCHEMBL24352251 | 0.75 | ASIC3 (0.44) | — | |
| SCHEMBL24352625 | 0.75 | ALOX5AP (0.40) | FEN1ADRA2C | |
| SCHEMBL24352279 | 0.74 | ADRA1A (0.43) | ADRA1DADRA1AADORA2AFEN1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | CCNT1 4076/4885CCNA2 3949/4885CDK2 2947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.