SCHEMBL31019977

SCHEMBL31019977

CNCc1ccccc1-c1cnnnn1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 1/20 0.44
▸ SLC6A4 P31645 6/20 0.37
▸ SLC6A2 P23975 5/20 0.37
▸ SLC6A3 Q01959 5/20 0.37
▸ CD274 Q9NZQ7 2/20 0.36
▸ SOS1 Q07889 5/20 0.34
▸ HTR2A P28223 1/20 0.33
▸ IFNAR1 P17181 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24352277 0.75 LTA4H (0.45) LTA4HSLC6A4SLC6A2SLC6A3SOS1
SCHEMBL22910530 0.71 LTA4H (0.47) LTA4HKDM4EMAPTALDH1A1CYP1A2
SCHEMBL24352870 0.69 ADRA1D (0.46) LTA4HSLC6A4SLC6A2SLC6A3CD274
SCHEMBL24352873 0.69 LTA4H (0.45) LTA4HSLC6A4SLC6A2SLC6A3CD274
SCHEMBL24352409 0.68 LTA4H (0.44) LTA4HSLC6A4SLC6A2SLC6A3CD274
SCHEMBL12017487 0.68 LTA4H (0.44) LTA4HSLC6A4SLC6A2SLC6A3CD274
SCHEMBL24352811 0.68 LTA4H (0.44) LTA4HSLC6A4SLC6A2SLC6A3CD274
SCHEMBL417693 0.67 LTA4H (0.55) LTA4HSLC6A4SLC6A2SLC6A3CD274
SCHEMBL31265560 0.67 SLC6A4 (0.57) LTA4HSLC6A4SLC6A2SLC6A3HTR2A
SCHEMBL8016874 0.67 SLC6A4 (0.57) LTA4HSLC6A4SLC6A2SLC6A3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658318-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING Synaffix B.V. (NL) 2025-12-10 — — EP disclosed
WO-2024160926-A1 HOMOGENEOUS ANTIBODY-CONJUGATES WITH HIGH PAYLOAD LOADING SYNAFFIX B.V. (NL) 2024-08-08 — — WO disclosed
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