Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24352233 | 0.83 | ADRA1D (0.43) | ADRA1DADRA1AADRA1BKMT2ACASP6 | |
| SCHEMBL9289349 | 0.81 | KMT2A (0.50) | ADRA1DADRA1AADRA1BKMT2ACASP6 | |
| SCHEMBL24352874 | 0.78 | LTA4H (0.38) | ADRA1DADRA1AADRA1BKMT2ALTA4H | |
| SCHEMBL22910530 | 0.72 | LTA4H (0.47) | ADRA1DADRA1AADRA1BLTA4HCASP6 | |
| SCHEMBL29767299 | 0.71 | KMT2A (0.55) | ADRA1DADRA1AADRA1BKMT2AMEN1 | |
| SCHEMBL16574032 | 0.71 | KMT2A (0.55) | ADRA1DADRA1AADRA1BKMT2AMEN1 | |
| SCHEMBL1095492 | 0.71 | KMT2A (0.55) | ADRA1DADRA1AADRA1BKMT2ACASP6 | |
| SCHEMBL24352277 | 0.70 | LTA4H (0.45) | LTA4HCASP6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL24352873 | 0.70 | LTA4H (0.45) | KMT2ALTA4HMEN1SLC6A4SLC6A2 | |
| SCHEMBL19589424 | 0.70 | MPO (0.46) | ADRA1DADRA1AADRA1BKMT2ACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | ADRA1D 646/4885ADRA1A 654/4885ADRA1B 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.