Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27299129 | 0.98 | ALDH1A1 (0.46) | ALDH1A1MAPK1POLBNR1I2TSHR | |
| SCHEMBL8627738 | 0.82 | POLB (0.46) | ALDH1A1MAPK1POLBNR1I2TSHR | |
| SCHEMBL7437555 | 0.82 | MTNR1A (0.49) | ALDH1A1MAPK1POLBNR1I2TSHR | |
| SCHEMBL28229438 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1POLBTSHRKDM4ELMNA | |
| SCHEMBL3662111 | 0.81 | SMN1; SMN2 (0.55) | ALDH1A1TSHRGLAKDM4EHPGD | |
| SCHEMBL5345206 | 0.81 | POLB (0.44) | ALDH1A1MAPK1POLBNR1I2TSHR | |
| SCHEMBL5792243 | 0.79 | POLB (0.43) | ALDH1A1MAPK1POLBNR1I2TSHR | |
| SCHEMBL27485398 | 0.79 | POLB (0.43) | ALDH1A1MAPK1POLBNR1I2TSHR | |
| Hydrochloric Acid SCHEMBL8159357 | 0.79 | POLB (0.43) | ALDH1A1MAPK1POLBNR1I2TSHR | |
| SCHEMBL28300016 | 0.79 | MLYCD (0.44) | ALDH1A1MAPK1POLBNR1I2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431171-A | Production method of L-p-hydroxyphenylglycine methyl ester | 山东优盈新材料有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119082247-A | Method for preparing cefprozil by using enzyme method | 华北制药河北华民药业有限责任公司 | 2024-12-06 | — | — | CN | claimed |
| CN-117720427-A | Recovery processing method of D-p-hydroxyphenylglycine methyl ester mother liquor | 山西双雁生物科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-116334054-A | Penicillin G acylase mutant | 上海邦林生物科技有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-105648022-B | A kind of technique that liquid 6-APA leads directly to Amoxicillin | 内蒙古常盛制药有限公司 | 2019-05-10 | — | — | CN | claimed |
| CN-107937472-A | A kind of method of straight-through synthesis Amoxicillin | 内蒙古常盛制药有限公司 | 2018-04-20 | — | — | CN | claimed |
| US-8541199-B2 | Mutant penicillin G acylases | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2013-09-24 | — | — | US | claimed |
| EP-2173892-B8 | Process for the preparation of immobilised recombinant Penicillin Acylase biocatalyst from Achromobacter sp CCM 4824 expressed in E. coli BL21 CCM 7394 and its use for the synthesis of beta-lactam antiobiotics | FERMENTA BIOTECH LTD (IN) | 2012-08-01 | — | — | EP | claimed |
| EP-2173892-B1 | Process for the preparation of penicillin or cephalosporin antibiotics | FERMENTA BIOTECH LTD (IN) | 2011-09-21 | — | — | EP | claimed |
| EP-2173892-A1 | PROCESS FOR THE PREPARATION OF IMMOBILIZED RECOMBINANT PENICILLIN ACYLASE CATALYST FROM ACHROMOBACTER SP. CCM 4824 EXPRESSED IN E. COLI BL 21 CCM 7394 AND ITS USE FOR THE SYNTHESIS OF BETA-LACTAM ANTIBIOTICS | Fermenta Biotech Limited (IN) | 2010-04-14 | — | — | EP | claimed |
| WO-2009016642-A1 | PROCESS FOR THE PREPARATION OF IMMOBILIZED RECOMBINANT PENICILLIN ACYLASE CATALYST FROM ACHROMOBACTER SP. CCM 4824 EXPRESSED IN E. COLI BL 21 CCM 7394 AND ITS USE FOR THE SYNTHESIS OF BETA-LACTAM ANTIBIOTICS | FERMENTA BIOTECH LIMITED (IN) | 2009-02-05 | — | — | WO | claimed |
| CN-121949137-A | Method for synthesizing L-hydroxyphenylglycine methyl ester by solid alkaline catalysis | 中国科学技术大学 | 2026-05-01 | — | — | CN | disclosed |
| CN-121949137-A | Method for synthesizing L-hydroxyphenylglycine methyl ester by solid alkaline catalysis | 中国科学技术大学 | 2026-05-01 | — | — | CN | disclosed |
| CN-223760446-U | Device for recycling levorotatory p-hydroxyphenylglycine methyl ester drying tail gas | 新天地药业股份有限公司 | 2026-01-06 | — | — | CN | disclosed |
| CN-119932000-A | Penicillin G acylase AxPGA mutant, expression plasmid, genetically engineered bacterium and application | 浙江昂利康制药股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| EP-0934262-A1 | BETA-THIOPROPIONYL-AMINO ACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1999020786-A1 | PROCESS FOR THE PREPARATION OF A β-LACTAM ANTIBIOTIC | DSM N.V. (NL) | 1999-04-29 | — | — | WO | disclosed |
| WO-1998017639-A1 | BETA-THIOPROPIONYL-AMINO ACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1998-04-30 | — | — | WO | disclosed |
| EP-0158340-A2 | Novel 1,5-benzothiazepine derivative, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-10-16 | — | — | EP | disclosed |
| US-4238306-A | Electrodialysis process for the separation of non-essential amino acids from derivatives thereof | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1980-12-09 | — | — | US | disclosed |