SCHEMBL2435528

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2430177	0.84	CNR1 (0.40)	CNR1CNR2ADRB3DYRK1AALDH1A1
	SCHEMBL2429943	0.83	DYRK1A (0.45)	CNR1CNR2DYRK1AALDH1A1KDM4E
	SCHEMBL2429759	0.81	CYP3A4 (0.50)	CNR1CNR2DYRK1AALDH1A1KDM4E
	SCHEMBL2432181	0.81	HPGD (0.43)	CNR1CNR2ADRB3DYRK1AALDH1A1
	SCHEMBL2465957	0.80	IMPDH2 (0.44)	CNR1CNR2ADRB3DYRK1AALDH1A1
	SCHEMBL2433772	0.79	BRD4 (0.47)	CNR1CNR2DYRK1AALDH1A1KDM4E
	SCHEMBL2429806	0.77	PDE5A (0.44)	CNR1CNR2ALDH1A1KDM4EHPGD
	SCHEMBL2434684	0.77	CNR1 (0.42)	CNR1CNR2ADRB3DYRK1AALDH1A1
	SCHEMBL2429913	0.77	NR3C1 (0.48)	CNR1CNR2ADRB3DYRK1AALDH1A1
	SCHEMBL2431938	0.77	CNR1 (0.42)	CNR1CNR2ADRB3DYRK1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.