SCHEMBL2433772

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2429943	0.89	DYRK1A (0.45)	KDM4EALDH1A1HPGDKDRPDGFRB
	SCHEMBL2428424	0.87	ALDH1A1 (0.46)	KDM4EALDH1A1HPGDGSK3BDYRK1A
	SCHEMBL2429913	0.85	NR3C1 (0.48)	KDM4EALDH1A1HPGDGSK3BDYRK1A
	SCHEMBL2432181	0.84	HPGD (0.43)	KDM4EALDH1A1HPGDKDRFLT3
	SCHEMBL2434710	0.82	KDM4E (0.44)	KDM4EALDH1A1HPGDGSK3BDYRK1A
	SCHEMBL2428415	0.82	ADORA3 (0.44)	KDM4EALDH1A1HPGDKITGSK3B
	SCHEMBL2429759	0.82	CYP3A4 (0.50)	KDM4EALDH1A1HPGDKITADORA3
	SCHEMBL2430177	0.81	CNR1 (0.40)	KDM4EALDH1A1HPGDEGFRDYRK1A
	SCHEMBL2465957	0.81	IMPDH2 (0.44)	KDM4EALDH1A1HPGDCDK2GSK3B
	SCHEMBL2433221	0.79	CNR1 (0.41)	KDM4EALDH1A1HPGDGSK3BADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.