SCHEMBL2429913

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2428424	0.90	ALDH1A1 (0.46)	NR3C1PGRNR3C2ARALDH1A1
	SCHEMBL2429806	0.88	PDE5A (0.44)	ALDH1A1HPGDKDM4ECNR2CNR1
	SCHEMBL2428415	0.87	ADORA3 (0.44)	NR3C1PGRNR3C2ARALDH1A1
	SCHEMBL2434710	0.87	KDM4E (0.44)	NR3C1PGRNR3C2ARALDH1A1
	SCHEMBL2434470	0.86	CNR1 (0.42)	ALDH1A1HPGDKDM4ECNR2CNR1
	SCHEMBL2432838	0.85	HTR7 (0.42)	NR3C1PGRNR3C2ARALDH1A1
	SCHEMBL2433772	0.85	BRD4 (0.47)	ALDH1A1HPGDKDM4ECNR2CNR1
	SCHEMBL2429943	0.85	DYRK1A (0.45)	NR3C1ALDH1A1HPGDKDM4ECNR2
	SCHEMBL2432181	0.84	HPGD (0.43)	ALDH1A1HPGDKDM4ECNR2CNR1
	SCHEMBL2465056	0.83	KDM4E (0.47)	ARALDH1A1HPGDKDM4ECNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.