Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24357079 | 0.92 | KDM4E (0.30) | ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30031262 | 0.78 | AADAT (0.34) | ALDH1A1KDM4EMAPTTP53RXFP1 | |
| SCHEMBL24357393 | 0.77 | CNR2 (0.35) | ALDH1A1KDM4EGAA | |
| SCHEMBL30031244 | 0.77 | KMT2A (0.34) | ALDH1A1HPGDGABRG2GABRB3GABRA3 | |
| SCHEMBL30031479 | 0.72 | AADAT (0.35) | ALDH1A1KDM4EMAPTTP53RXFP1 | |
| SCHEMBL30031902 | 0.72 | MEN1 (0.40) | ALDH1A1KDM4EMAPTCYP3A4TP53 | |
| SCHEMBL30032108 | 0.71 | AADAT (0.36) | ALDH1A1KDM4EMAPTTP53RXFP1 | |
| SCHEMBL30031815 | 0.71 | TP53 (0.36) | MAPTTP53RXFP1 | |
| SCHEMBL22236137 | 0.70 | GABRG2 (0.41) | ALDH1A1HPGDGABRG2GABRB3GABRA3 | |
| SCHEMBL30031744 | 0.70 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220125771-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220125771-A1 | SUBSTITUTED POLYCYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | SLC10A1, NR1H4, HDGF | ALDH1A1 2459/4885HPGD 774/4885GABRG2 2687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.