SCHEMBL24360323

SCHEMBL24360323

CC(=O)N(C(=O)OC(C)(C)C)[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.47
DNMT1 P26358 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24360324 1.00 KIF11 (0.47) KIF11DNMT1
SCHEMBL28768828 0.88 KIF11 (0.48) KIF11DNMT1
SCHEMBL26923900 0.87 KIF11 (0.40) KIF11DNMT1
SCHEMBL24360332 0.86 KIF11 (0.40) KIF11DNMT1
SCHEMBL24374519 0.86 KIF11 (0.40) KIF11DNMT1
SCHEMBL8370224 0.85 KIF11 (0.49) KIF11DNMT1
SCHEMBL21084958 0.85 KIF11 (0.49) KIF11DNMT1
SCHEMBL20185747 0.85 KIF11 (0.49) KIF11DNMT1
SCHEMBL31599210 0.84 KIF11 (0.44) KIF11DNMT1
SCHEMBL24360331 0.82 KIF11 (0.46) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399317-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2023-12-14 US disclosed
US-20230399317-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2023-12-14 US disclosed
EP-4232034-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS AZURA OPHTHALMICS LTD (IL) 2023-08-30 EP disclosed
CN-116670116-A Compounds and methods for treating ocular disorders 阿祖拉眼科有限公司 2023-08-29 CN disclosed
CN-116635032-A Compounds and methods for treating ocular disorders 阿祖拉眼科有限公司 2023-08-22 CN disclosed
WO-2022084739-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2022-04-28 WO disclosed
WO-2022084739-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2022-04-28 WO disclosed
WO-2022084747-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS Azura Ophthalmics Ltd. (IL) 2022-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399317-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS MPO, MUC1, CRYAB KIF11 1650/4885DNMT1 3762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.