SCHEMBL883130

SCHEMBL883130

COC(=O)c1ccc(Oc2cccc(C(=O)OC)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.60
PARP15 Q460N3 1/20 0.60
PARP14 Q460N5 1/20 0.60
PARP10 Q53GL7 1/20 0.60
TNKS2 Q9H2K2 1/20 0.60
PARP2 Q9UGN5 1/20 0.60
RAB9A P51151 4/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
NPC1 O15118 3/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
POLB P06746 1/20 0.58
BLM P54132 1/20 0.58
TP53 P04637 2/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 2/20 0.57
PKM P14618 1/20 0.57
HPGD P15428 1/20 0.57
MAPK1 P28482 1/20 0.57
CA1 P00915 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2436534 0.93 L3MBTL1 (0.65) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL13087758 0.92 AKR1C3 (0.65) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL31657173 0.92 AKR1C3 (0.70) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL521860 0.91 AKR1C3 (0.68) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL14217726 0.90 L3MBTL1 (0.56) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL12260934 0.89 L3MBTL1 (0.55) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL5873911 0.89 SMN1; SMN2 (0.58) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL27149873 0.89 L3MBTL1 (0.55) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL11494980 0.89 L3MBTL1 (0.55) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL8569015 0.87 CA1 (0.55) TNKSPARP15PARP14PARP10TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4516835-A1 SEMI-AROMATIC POLYESTER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Zhuhai Kingfa Biomaterial Co., Ltd. (CN) 2025-03-05 EP disclosed
US-20250043069-A1 SEMI-AROMATIC POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF JIANGSU KINGFA SCI & TECH. ADVANCED MATERIALS CO., LTD. (CN) 2025-02-06 US disclosed
EP-4174105-B1 SEMI-AROMATIC POLYESTER AND PREPARATION METHOD AND APPLICATION THEREOF JIANGSU KINGFA SCI & TECH ADV MAT CO LTD (CN) 2023-12-13 EP disclosed
EP-4174105-A1 SEMI-AROMATIC POLYESTER AND PREPARATION METHOD AND APPLICATION THEREOF Jiangsu Kingfa Sci. & Tech. Advanced Materials Co., Ltd. (CN) 2023-05-03 EP disclosed
CN-105392816-A Heat resistant polyethylene terephthalate and a process for the preparation of the same ESTER IND LTD 2016-03-09 CN disclosed
EP-2414350-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2014-11-12 EP disclosed
US-8796466-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2014-08-05 US disclosed
WO-2012039717-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2012-03-29 WO disclosed
US-20110237636-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-09-29 US disclosed
US-20110237636-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-09-29 US disclosed
US-20110077280-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237636-A1 Hepatitis C Virus Inhibitors HAVCR2, EIF2AK2, MAVS TNKS 3874/4885PARP15 4303/4885PARP14 4332/4885
US-20110077280-A1 Hepatitis C Virus Inhibitors HAVCR2, EIF2AK2, MAVS TNKS 3874/4885PARP15 4303/4885PARP14 4332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.