Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Tetracaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A known ✓ | Q14524 | 2/20 | 0.97 |
| ▸ | SCN1A known ✓ | P35498 | 2/20 | 0.97 |
| ▸ | SCN2A known ✓ | Q99250 | 2/20 | 0.97 |
| ▸ | SCN3A known ✓ | Q9NY46 | 2/20 | 0.97 |
| ▸ | SCN7A known ✓ | Q01118 | 1/20 | 0.97 |
| ▸ | SCN9A known ✓ | Q15858 | 1/20 | 0.97 |
| ▸ | SCN8A known ✓ | Q9UQD0 | 1/20 | 0.97 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.97 |
| ▸ | DRD3 | P35462 | 2/20 | 0.97 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.97 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.97 |
| ▸ | MAOA | P21397 | 1/20 | 0.97 |
| ▸ | CNR1 | P21554 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetracaine SCHEMBL1355595 | 1.00 | LMNA (1.00) | LMNABLMKDM4EGMNNRAB9A | |
| Tetracaine SCHEMBL34714 | 0.99 | LMNA (1.00) | LMNABLMKDM4EGMNNRAB9A | |
| Tetracaine SCHEMBL27896875 | 0.97 | LMNA (0.97) | LMNABLMKDM4EGMNNRAB9A | |
| Tetracaine SCHEMBL28641231 | 0.97 | LMNA (0.97) | LMNABLMKDM4EGMNNRAB9A | |
| Tetracaine SCHEMBL7774179 | 0.97 | LMNA (0.97) | LMNABLMKDM4EGMNNRAB9A | |
| Tetracaine SCHEMBL3176478 | 0.97 | LMNA (0.97) | LMNABLMKDM4EGMNNRAB9A | |
| Tetracaine SCHEMBL2728732 | 0.96 | LMNA (0.95) | LMNABLMKDM4EGMNNRAB9A | |
| Tetracaine SCHEMBL1652724 | 0.96 | LMNA (0.95) | LMNABLMKDM4EGMNNRAB9A | |
| Tetracaine SCHEMBL1840446 | 0.94 | LMNA (0.90) | LMNABLMKDM4EGMNNRAB9A | |
| SCHEMBL15412942 | 0.94 | LMNA (0.90) | LMNABLMKDM4EGMNNRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6003 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723819-B1 | WOUND DRESSING | ANIMAL ETHICS PTY LTD (AU) | 2026-04-22 | — | — | EP | claimed |
| US-20260097044-A1 | ION PAIR LIQUID CRYSTAL FORMULATIONS FOR LONG-ACTING INJECTABLES OF POORLY SOLUBLE DRUGS | FORDOZ PHARMA CORP. (US) | 2026-04-09 | — | — | US | claimed |
| US-12409155-B1 | Ready to use LET formulations | QuVa Pharma Inc. (US) | 2025-09-09 | — | — | US | claimed |
| EP-3876904-B1 | ORAL MUCOSAL CARRIER AND PROTECTANT | INSPIRED MAT STRATEGIES LLC (US) | 2025-08-20 | — | — | EP | claimed |
| CN-119925714-A | Soft tissue filling preparation containing calcium oxalate particles, preparation method and application thereof | 常州药物研究所有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119896765-A | Composite solution containing hydroxyapatite microsphere for injection, preparation method and application thereof | 常州药物研究所有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119746710-A | Medical hpv-resistant human body lubricant, processing method and device | 苏州复大生物医学科技有限公司 | 2025-04-04 | — | — | CN | claimed |
| WO-2025060858-A1 | COMPOSITE GEL CONTAINING CALCIUM HYDROXYAPATITE MICROSPHERES HAVING A CORE-SHELL STRUCTURE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 合肥启灏医疗科技有限公司 | 2025-03-27 | — | — | WO | claimed |
| CN-119367266-A | Method for preparing sterile compound multi-adhesive product and integrated production equipment thereof | 山东序列生物科技有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-119345187-A | Surface anesthetic with effects of adhesion to oral mucosa, anti-salivation and taste improvement, and its preparation method | 山东大学第二医院 | 2025-01-24 | — | — | CN | claimed |
| US-4906670-A | Pharmaceutical composition for the treatment of periodontal disease | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 1990-03-06 | — | — | US | claimed |
| CN-1036327-A | A kind of compound method of indometacin gel | GEN HOSPITAL OF JINAN MILITARY (CN) | 1989-10-18 | — | — | CN | claimed |
| WO-1989000047-A1 | HEMORRHOIDAL, OTHER COMPOSITIONS AND METHODS OF TREATMENT | PACKMAN ELIAS W (US) | 1989-01-12 | — | — | WO | claimed |
| US-4741899-A | Process for arresting the proliferation of organisms that convert axillary secretions to malodorous materials | BRISTOL-MYERS COMPANY (US) | 1988-05-03 | — | — | US | claimed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | claimed |
| EP-0126684-A2 | Drug delivery system utilizing thermosetting gels | MERCK & CO. INC. (US) | 1984-11-28 | — | — | EP | claimed |
| US-4474751-A | SUSTAINED RELEASE USING AN ALKYLENEDIAMINE-MODIFIED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER | MERCK & CO., INC. (US) | 1984-10-02 | — | — | US | claimed |
| US-4312865-A | Medication having penetration through cutaneous surfaces into articular and muscular areas | SZUCS MURRILL M | 1982-01-26 | — | — | US | claimed |
| US-4265883-A | AMMONIUM AND POTASSIUM ALUMINUM SULFATES | CAMERON, RAPHAEL MORRIS, 7207 S. BENNETT AVE., CHICAGO, IL | 1981-05-05 | — | — | US | claimed |
| US-4164559-A | CARRIER MEMBRANE FOR OPHTHALMIC MEDICATION | CORNELL RESEARCH FOUNDATION, INC. (US) | 1979-08-14 | — | — | US | claimed |