Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 4/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372557 | 0.95 | MGLL (0.44) | LMNATDP1FFAR1MGLLHDAC2 | |
| SCHEMBL24372734 | 0.90 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1TDP1FFAR1 | |
| SCHEMBL24372550 | 0.83 | CYP1A2 (0.53) | LMNASMN1; SMN2ALDH1A1TDP1NPC1 | |
| SCHEMBL24372552 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TDP1FFAR1 | |
| SCHEMBL4457866 | 0.78 | TDP1 (0.56) | LMNASMN1; SMN2ALDH1A1TDP1FFAR1 | |
| SCHEMBL24372731 | 0.78 | MGLL (0.46) | FFAR1MGLLHDAC2 | |
| SCHEMBL24372556 | 0.78 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1TDP1FFAR1 | |
| SCHEMBL24372546 | 0.76 | L3MBTL1 (0.44) | ALDH1A1TDP1FFAR1NPC1RAB9A | |
| SCHEMBL12808247 | 0.75 | LMNA (0.59) | LMNASMN1; SMN2ALDH1A1FFAR1NPC1 | |
| SCHEMBL28721829 | 0.74 | TDP1 (0.63) | LMNASMN1; SMN2ALDH1A1TDP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | L1CAM, EPCAM, SELPLG | LMNA 1891/4885SMN1; SMN2 4648/4885ALDH1A1 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.