Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24372731 | 0.95 | MGLL (0.46) | MGLLFFAR1HDAC2HDAC1 | |
| SCHEMBL24372556 | 0.93 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1FFAR1TDP1 | |
| SCHEMBL24372734 | 0.92 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1MGLLFFAR1 | |
| SCHEMBL24373015 | 0.88 | FFAR1 (0.45) | LMNASMN1; SMN2ALDH1A1FFAR1TDP1 | |
| SCHEMBL12112846 | 0.85 | TDP1 (0.54) | MGLLFFAR1TDP1 | |
| SCHEMBL24372603 | 0.84 | PPARG (0.36) | LMNASMN1; SMN2ALDH1A1MGLLKDM4E | |
| SCHEMBL24372545 | 0.83 | ALDH1A1 (0.46) | LMNASMN1; SMN2ALDH1A1FFAR1NPC1 | |
| SCHEMBL24372549 | 0.83 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1MGLLFFAR1 | |
| SCHEMBL279288 | 0.82 | LMNA (0.46) | LMNASMN1; SMN2MGLLFFAR1HDAC2 | |
| SCHEMBL2602486 | 0.81 | THRB (0.49) | LMNASMN1; SMN2ALDH1A1MGLLFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127286-A1 | LIGANDS FOR NANO-SIZED MATERIALS | L1CAM, EPCAM, SELPLG | LMNA 1891/4885SMN1; SMN2 4648/4885ALDH1A1 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.