SCHEMBL24372585

SCHEMBL24372585

CC1(C)c2ccccc2-c2ccc(N(c3ccc4ccc5c6ccccc6ccc5c4c3)c3ccc4oc5ccccc5c4c3)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.34
KDM4E B2RXH2 8/20 0.34
HPGD P15428 5/20 0.34
MAPT P10636 5/20 0.34
GLA P06280 3/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 2/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAOB P27338 1/20 0.34
SIRT2 Q8IXJ6 2/20 0.33
SIRT1 Q96EB6 2/20 0.33
HNF4A P41235 1/20 0.33
ALK Q9UM73 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26060399 0.97 ALDH1A1 (0.34) ALDH1A1KDM4EHPGDMAPTGLA
SCHEMBL26059913 0.96 AHR (0.33) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL26060033 0.94 HSP90AA1 (0.32) ALDH1A1KDM4EHPGDMAPTGLA
SCHEMBL26059691 0.94 ALDH1A1 (0.35) ALDH1A1KDM4EHPGDMAPTGLA
SCHEMBL26059304 0.93 ALDH1A1 (0.34) ALDH1A1KDM4EHPGDMAPTGLA
SCHEMBL16883042 0.92 MAPT (0.36) ALDH1A1KDM4EHPGDMAPTNPC1
SCHEMBL27048452 0.92 PGR (0.32) ALDH1A1KDM4EHPGDMAPTGLA
SCHEMBL26059398 0.92 ALDH1A1 (0.33) ALDH1A1KDM4EHPGDMAPTGLA
SCHEMBL16773277 0.92 HSP90AA1 (0.33) ALDH1A1KDM4EHPGDMAPTGLA
SCHEMBL24887203 0.92 ALOX5 (0.34) ALDH1A1KDM4EHPGDMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-28 US disclosed
US-9682952-B2 Isotopologues of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl) piperidine-2-6-dione and methods of preparation thereof CELGENE CORPORATION (US) 2017-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, TERT, LIMS1 ALDH1A1 275/4885KDM4E 3373/4885HPGD 4072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.