Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | UQCRB | P14927 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437114 | 0.95 | RORA (0.39) | HSD11B1RORAALDH1A1HSD17B2HSD17B3 | |
| SCHEMBL2443803 | 0.89 | PTPN1 (0.34) | HSD11B1NR1H3 | |
| Trifluoromethanesulfonic Acid SCHEMBL51512 | 0.84 | HSD11B1 (0.41) | HSD11B1RORAALDH1A1HSD17B2HSD17B3 | |
| Trifluoromethanesulfonic Acid SCHEMBL3136704 | 0.84 | HSD11B1 (0.41) | HSD11B1RORAALDH1A1HSD17B2HSD17B3 | |
| SCHEMBL2437122 | 0.83 | HSD11B1 (0.40) | HSD11B1RORAALDH1A1HSD17B2HSD17B3 | |
| SCHEMBL1477345 | 0.83 | ALDH1A1 (0.40) | HSD11B1ALDH1A1HSD17B2HSD17B3UQCRB | |
| SCHEMBL29745785 | 0.83 | HSD11B1 (0.40) | HSD11B1RORAALDH1A1HSD17B2HSD17B3 | |
| SCHEMBL2286473 | 0.83 | ALDH1A1 (0.40) | HSD11B1ALDH1A1HSD17B2HSD17B3UQCRB | |
| SCHEMBL2435494 | 0.81 | HSD11B1 (0.38) | HSD11B1RORAALDH1A1HSD17B2HSD17B3 | |
| SCHEMBL2438820 | 0.81 | HSD11B1 (0.38) | HSD11B1RORAALDH1A1HSD17B2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078028-B1 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA (US) | 2011-09-07 | — | — | EP | claimed |