SCHEMBL24379977

SCHEMBL24379977

CCNC(CCCCN)C(=O)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.41
SIRT6 Q8N6T7 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
CPB2 Q96IY4 7/20 0.38
GNAI3 P08754 1/20 0.36
GNAO1 P09471 1/20 0.36
GNAI1 P63096 1/20 0.36
GSR P00390 1/20 0.36
SLC6A5 Q9Y345 1/20 0.36
TLR2 O60603 1/20 0.36
RNPEP Q9H4A4 1/20 0.35
DPP8 Q6V1X1 1/20 0.34
DPP9 Q86TI2 1/20 0.34
DPP7 Q9UHL4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13891963 0.82 FOLH1 (0.40) FOLH1SIRT6SIRT1CPB2GNAI3
SCHEMBL25570523 0.82 FOLH1 (0.40) FOLH1SIRT6SIRT1CPB2GNAI3
SCHEMBL22375523 0.82 FOLH1 (0.40) FOLH1SIRT6SIRT1CPB2GNAI3
SCHEMBL10047161 0.82 FOLH1 (0.40) FOLH1SIRT6SIRT1CPB2GNAI3
SCHEMBL22859968 0.82 FOLH1 (0.40) FOLH1SIRT6SIRT1CPB2GNAI3
SCHEMBL21400200 0.81 FFAR4 (0.42) FOLH1TLR2
SCHEMBL19483432 0.81 CPB2 (0.41) FOLH1SIRT6SIRT1CPB2GNAI3
SCHEMBL19483433 0.81 CPB2 (0.41) FOLH1SIRT6SIRT1CPB2GNAI3
SCHEMBL20402783 0.81 CPB2 (0.41) FOLH1SIRT6SIRT1CPB2GNAI3
SCHEMBL16383761 0.80 SIRT6 (0.45) FOLH1SIRT6SIRT1CPB2GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319540-B2 HIF 1-alpha antisense oligonucleotides OLIPASS CORPORATION (KR) 2022-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319540-B2 HIF 1-alpha antisense oligonucleotides HIF1A, HIF1AN, UPF1 FOLH1 890/4885SIRT6 2791/4885SIRT1 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.