SCHEMBL24384183

SCHEMBL24384183

COc1ccc(I)cc1NCCCS(=O)(=O)OCC(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
POLB P06746 1/20 0.34
LMNA P02545 3/20 0.34
TSHR P16473 2/20 0.34
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
BRAF P15056 2/20 0.34
TNNI3K Q59H18 2/20 0.34
KMT2A Q03164 3/20 0.33
WDR5 P61964 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP17A1 P05093 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
GAA P10253 1/20 0.31
MAPK1 P28482 2/20 0.31
MEN1 O00255 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24384200 0.76 SIGMAR1 (0.31) KMT2A
SCHEMBL24384166 0.75 ALDH1A1 (0.33) ALDH1A1
SCHEMBL27873244 0.73 LMNA (0.43) MAPTPOLBLMNATSHRHTT
SCHEMBL777918 0.64 CA1 (0.52) HTT
SCHEMBL6674338 0.64 ALDH1A1 (0.42) MAPTLMNAHTTSMN1; SMN2KMT2A
SCHEMBL24384181 0.64 MAPT (0.44) MAPTPOLBLMNATSHRHTT
SCHEMBL24384238 0.63 KMT2A (0.31) KMT2A
SCHEMBL11614972 0.63 LMNA (0.47) MAPTPOLBLMNATSHRHTT
SCHEMBL11314106 0.62 TSHR (0.51) MAPTPOLBLMNATSHRHTT
SCHEMBL31204162 0.61 CA1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382928-A1 EUROPIUM(III) COMPLEXES AS PH SENSORS CISBIO BIOASSAYS (FR) 2023-11-30 US disclosed
US-20230382928-A1 EUROPIUM(III) COMPLEXES AS PH SENSORS CISBIO BIOASSAYS (FR) 2023-11-30 US disclosed
WO-2022090284-A1 EUROPIUM(III) COMPLEXES AS PH SENSORS CISBIO BIOASSAYS (FR) 2022-05-05 WO disclosed
EP-3992182-A1 EUROPIUM(III) COMPLEXES AS PH SENSORS Cisbio Bioassays (FR) 2022-05-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382928-A1 EUROPIUM(III) COMPLEXES AS PH SENSORS NCS1, GALR3, TAS1R3 MAPT 2123/4885POLB 3165/4885LMNA 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.