Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493641 | 0.85 | NPC1 (0.47) | GPR119NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL493936 | 0.85 | KIF11 (0.45) | LMNATHRBS1PR1S1PR3CNR1 | |
| SCHEMBL19835582 | 0.82 | GPR119 (0.39) | GPR119NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL24386453 | 0.78 | GPR119 (0.37) | GPR119KMONPSR1KCNH2 | |
| SCHEMBL2740475 | 0.75 | NPC1 (0.40) | NPC1RAB9AKMOTP53TSHR | |
| SCHEMBL6854121 | 0.75 | NPC1 (0.43) | NPC1RAB9ALMNAL3MBTL1KMO | |
| SCHEMBL24386337 | 0.72 | CES1 (0.44) | GPR119HDAC1HDAC6 | |
| SCHEMBL30584973 | 0.72 | KMO (0.41) | GPR119KMOPPARAKAT6AKCNH2 | |
| SCHEMBL24386076 | 0.71 | SCN5A (0.46) | GPR119NPC1RAB9AMAPTS1PR1 | |
| SCHEMBL16907809 | 0.71 | NR1H4 (0.44) | NPC1RAB9AL3MBTL1KMOTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3275440-B1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2022-05-04 | — | — | EP | disclosed |