Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24386409 | 0.85 | GPR119 (0.37) | LMNATHRBS1PR1S1PR3CNR1 | |
| SCHEMBL28601834 | 0.83 | PTGS2 (0.48) | LMNATHRBS1PR1S1PR3 | |
| SCHEMBL19836179 | 0.81 | S1PR1 (0.41) | S1PR1S1PR3CNR1KCNH2NOTUM | |
| SCHEMBL493641 | 0.81 | NPC1 (0.47) | KIF11LMNA | |
| SCHEMBL30516088 | 0.80 | CNR1 (0.38) | KIF11S1PR1S1PR3CNR1KCNH2 | |
| SCHEMBL30006227 | 0.80 | LMNA (0.53) | LMNATHRB | |
| SCHEMBL2106230 | 0.79 | NOTUM (0.50) | S1PR1CASP3NOTUM | |
| SCHEMBL29808202 | 0.79 | NOTUM (0.50) | S1PR1CASP3NOTUM | |
| SCHEMBL19835582 | 0.78 | GPR119 (0.39) | LMNA | |
| SCHEMBL2740475 | 0.78 | NPC1 (0.40) | SIRT2CASP3AHRNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635397-B | Preparation and application of 3- (4-trifluoromethylphenyl) -1,2,4-oxadiazole derivative containing five-membered nitrogen heterocycle | 南通大学 | 2022-10-25 | — | — | CN | claimed |
| CN-111635397-A | Preparation and application of 3- (4-trifluoromethylphenyl) -1,2, 4-oxadiazole derivative containing five-membered nitrogen heterocycle | 南通大学 | 2020-09-08 | — | — | CN | claimed |
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | TAXIS PHARMACEUTICALS, INC. (US) | 2025-06-05 | — | — | US | disclosed |
| CN-118265453-A | Protein aggregation inhibiting compounds for plant disease control | 马克斯·普朗克科学促进学会 | 2024-06-28 | — | — | CN | disclosed |
| CN-112300145-B | Tri-aromatic ring compound targeting STAT3 bifunctional phosphorylation site and application thereof | 上海宇耀生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-111635397-B | Preparation and application of 3- (4-trifluoromethylphenyl) -1,2,4-oxadiazole derivative containing five-membered nitrogen heterocycle | 南通大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-111635397-B | Preparation and application of 3- (4-trifluoromethylphenyl) -1,2,4-oxadiazole derivative containing five-membered nitrogen heterocycle | 南通大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-111635397-B | Preparation and application of 3- (4-trifluoromethylphenyl) -1,2,4-oxadiazole derivative containing five-membered nitrogen heterocycle | 南通大学 | 2022-10-25 | — | — | CN | disclosed |
| EP-3275440-B1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2022-05-04 | — | — | EP | disclosed |
| CN-111635397-A | Preparation and application of 3- (4-trifluoromethylphenyl) -1,2, 4-oxadiazole derivative containing five-membered nitrogen heterocycle | 南通大学 | 2020-09-08 | — | — | CN | disclosed |
| CN-111635397-A | Preparation and application of 3- (4-trifluoromethylphenyl) -1,2, 4-oxadiazole derivative containing five-membered nitrogen heterocycle | 南通大学 | 2020-09-08 | — | — | CN | disclosed |
| CN-111635397-A | Preparation and application of 3- (4-trifluoromethylphenyl) -1,2, 4-oxadiazole derivative containing five-membered nitrogen heterocycle | 南通大学 | 2020-09-08 | — | — | CN | disclosed |
| EP-3275440-A1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | National Center for Geriatrics and Gerontology (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | KIF11 2463/4885LMNA 2485/4885THRB 3770/4885 |
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | KIF11 4421/4885LMNA 1817/4885THRB 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.