Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.52 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.52 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22256436 | 0.92 | FGFR1 (0.57) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL22256427 | 0.90 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL22256471 | 0.84 | SLC6A3 (0.57) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL24390974 | 0.83 | TSHR (0.57) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL17372744 | 0.82 | MAPT (0.60) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL4957139 | 0.82 | FABP4 (0.56) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL22256428 | 0.82 | MAPT (0.54) | FGFR1FGFR2FGFR4FGFR3MEN1 | |
| SCHEMBL30285287 | 0.79 | SLC6A3 (0.71) | MEN1MAPTKMT2ATSHRHTT | |
| SCHEMBL22256467 | 0.79 | EGFR (0.54) | MEN1MAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL22256466 | 0.78 | HDAC7 (0.49) | MEN1MAPTKMT2AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220140245-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220140245-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, NES, ILK | FGFR1 1695/4885FGFR2 1889/4885FGFR4 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.