Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.41 |
| ▸ | LOX | P28300 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375266 | 0.84 | ST14 (0.50) | LOXL2LOXMRGPRX4TRPV4SCN9A | |
| SCHEMBL24400400 | 0.82 | LOXL2 (0.40) | LOXL2LOXMRGPRX4TRPV4SCN9A | |
| SCHEMBL4371648 | 0.81 | MAOB (0.54) | SCN9AMAOB | |
| SCHEMBL18233500 | 0.78 | LOXL2 (0.51) | LOXL2LOXMRGPRX4SCN9APLAAT3 | |
| SCHEMBL29404783 | 0.78 | LOXL2 (0.53) | LOXL2LOXTRPV4MAOBDAO | |
| SCHEMBL40545 | 0.78 | LOXL2 (0.53) | LOXL2LOXTRPV4MAOBDAO | |
| Hydrochloric Acid SCHEMBL3494124 | 0.77 | LOXL2 (0.55) | LOXL2LOXTRPV4CHRNB2CHRNA4 | |
| SCHEMBL25383135 | 0.72 | ALDH1A1 (0.50) | TRPV4SCN9APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9900498 | 0.72 | SCN9A (0.49) | MRGPRX4TRPV4SCN9APLAAT3PLAAT5 | |
| SCHEMBL23207502 | 0.71 | CHRNB2 (0.45) | LOXL2MRGPRX4TRPV4SCN9APLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238974-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022089454-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |