Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 7/20 | 0.34 |
| ▸ | CNR2 | P34972 | 6/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22393853 | 1.00 | RORC (0.41) | RORCNUDT1BACE1TSHRCNR1 | |
| SCHEMBL22214041 | 0.85 | HSP90AA1 (0.40) | NUDT1BACE1CNR1CNR2HSP90AA1 | |
| SCHEMBL22393944 | 0.85 | HSP90AA1 (0.40) | NUDT1BACE1CNR1CNR2HSP90AA1 | |
| SCHEMBL23484456 | 0.85 | HSP90AA1 (0.40) | NUDT1BACE1CNR1CNR2HSP90AA1 | |
| SCHEMBL22295956 | 0.85 | HSP90AA1 (0.40) | NUDT1BACE1CNR1CNR2HSP90AA1 | |
| SCHEMBL23425688 | 0.82 | NUDT1 (0.36) | NUDT1BACE1CNR1CNR2HSP90AA1 | |
| SCHEMBL24962101 | 0.77 | NUDT1 (0.42) | NUDT1BACE1CNR1CNR2HSP90AA1 | |
| SCHEMBL16014088 | 0.76 | NUDT1 (0.45) | NUDT1BACE1CNR1CNR2HSP90AA1 | |
| SCHEMBL21630423 | 0.75 | ACMSD (0.49) | RORCNUDT1BACE1TSHRADRB2 | |
| SCHEMBL22471698 | 0.75 | ACMSD (0.49) | RORCNUDT1BACE1TSHRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11326165-B1 | Methods and compositions for modulating splicing | SKYHAWK THERAPEUTICS, INC. (US) | 2022-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11326165-B1 | Methods and compositions for modulating splicing | RBM17, SF3B1, SNRPA1 | RORC 2190/4885NUDT1 1330/4885BACE1 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.