Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21695739 | 0.93 | S1PR1 (0.36) | S1PR1TRPA1ATMESR1ESR2 | |
| SCHEMBL24404669 | 0.84 | TSHR (0.42) | S1PR1TSHRACHEALDH1A1MEN1 | |
| SCHEMBL22941836 | 0.79 | ESR1 (0.41) | TRPA1ATMESR1ESR2ALDH1A1 | |
| SCHEMBL585558 | 0.79 | TRPA1 (0.46) | TRPA1ATMESR1ESR2TSHR | |
| SCHEMBL21085223 | 0.79 | HSD17B1 (0.33) | ACHEMEN1KMT2ACYP1A2CYP2A6 | |
| SCHEMBL25446015 | 0.78 | MAPT (0.40) | S1PR1TSHRACHEALDH1A1MEN1 | |
| SCHEMBL7890806 | 0.78 | ALDH1A1 (0.38) | TRPA1ATMESR1ESR2TSHR | |
| SCHEMBL8322304 | 0.77 | S1PR1 (0.40) | S1PR1ALDH1A1CYP1A2CYP2A6KDM1A | |
| SCHEMBL7764813 | 0.77 | CYP2A6 (0.44) | TSHRALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL7763414 | 0.76 | ALDH1A1 (0.43) | S1PR1TSHRACHEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617005-B1 | Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same | FUJI XEROX CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-5587263-A | STABLE CHARGE TRANSPORT LAYER | FUJI XEROX CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5495049-A | CHARGE TRANSFER COMPOUNDS | FUJI XEROX CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0617005-A2 | Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same | FUJI XEROX CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |