Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 13/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 5/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 4/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405723 | 0.78 | GAA (0.39) | GAATSHRNPC1LMNARAB9A | |
| SCHEMBL24405756 | 0.76 | GAA (0.39) | GAATSHRNPC1LMNARAB9A | |
| SCHEMBL21474179 | 0.76 | GAA (0.39) | CYP3A4CYP2D6GAATSHRNPC1 | |
| SCHEMBL23119712 | 0.74 | GAA (0.40) | GAATSHRNPC1LMNARAB9A | |
| SCHEMBL21474041 | 0.71 | MCHR1 (0.38) | GAATSHRNPC1LMNARAB9A | |
| SCHEMBL24405634 | 0.70 | ALDH1A1 (0.40) | GAATSHRNPC1LMNARAB9A | |
| SCHEMBL29026387 | 0.69 | PGR (0.38) | GAATSHRNPC1LMNARAB9A | |
| SCHEMBL24405889 | 0.69 | HCAR3 (0.45) | LMNARAB9ASMN1; SMN2TP53 | |
| SCHEMBL24405700 | 0.68 | NPEPPS (0.42) | GAATSHRNPC1LMNARAB9A | |
| SCHEMBL24405558 | 0.66 | PGR (0.43) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |