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Sugi Predict / Compounds / SCHEMBL24409120

SCHEMBL24409120

SCHEMBL24409120

Cc1nccc2c1OC1(CCN(C(=O)OC(C)(C)C)CC1)C2

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 12/20 0.45
▸ NAMPT P43490 5/20 0.42
▸ POLB P06746 1/20 0.41
▸ OPRD1 P41143 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ HRH3 Q9Y5N1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24408911 0.88 POLB (0.50) GPR119NAMPTPOLBOPRD1OPRK1
SCHEMBL24408910 0.85 GPR119 (0.47) GPR119NAMPT
SCHEMBL29634699 0.83 ACACB (0.35) HRH3
SCHEMBL22520476 0.80 GPR119 (0.52) GPR119NAMPTHRH3
SCHEMBL13161934 0.80 POLB (0.48) GPR119NAMPTPOLBOPRD1OPRK1
SCHEMBL29634691 0.77 GPR119 (0.54) GPR119NAMPTHRH3
SCHEMBL24408939 0.76 GPR119 (0.47) GPR119NAMPTHRH3
SCHEMBL17848653 0.76 GPR119 (0.54) GPR119HRH3
SCHEMBL31094899 0.76 GPR119 (0.54) GPR119HRH3
SCHEMBL24408862 0.76 POLB (0.49) GPR119POLBOPRD1OPRK1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022095971-A1 SPIRO HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 上海医药集团股份有限公司 2022-05-12 — — WO disclosed
WO-2022095971-A1 SPIRO HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 上海医药集团股份有限公司 2022-05-12 — — WO disclosed
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