SCHEMBL24413533

SCHEMBL24413533

O=C(Oc1ccc(Oc2ccc(I)cc2)cc1)C(F)(F)S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.46
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
PTPN1 P18031 1/20 0.36
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
CA12 O43570 1/20 0.34
ALDH1A1 P00352 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
POLB P06746 1/20 0.32
TBXA2R P21731 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24413785 0.93 ELANE (0.39) ELANECA1CA2CA9PTPN1
SCHEMBL24413615 0.87 ELANE (0.38) ELANEMMP2MMP9L3MBTL1SMN1; SMN2
SCHEMBL24413638 0.86 ELANE (0.40) ELANEMMP2MMP9POLBTBXA2R
SCHEMBL24413641 0.86 ELANE (0.47) ELANEPTPN1MMP2MMP9
SCHEMBL24414033 0.84 ELANE (0.44) ELANEPTPN1ALDH1A1TBXA2RMEN1
SCHEMBL24413720 0.84 PCNA (0.39) ELANESMN1; SMN2POLB
SCHEMBL24414011 0.84 ELANE (0.41) ELANEPTPN1ALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL24413654 0.83 THRB (0.41) ELANEALDH1A1L3MBTL1SMN1; SMN2POLB
SCHEMBL24413518 0.83 LMNA (0.35) ELANECA1CA2CA9MMP2
SCHEMBL27263062 0.82 ELANE (0.51) ELANEALDH1A1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, FGFR1, NHERF1 ELANE 1517/4885CA1 314/4885CA2 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.