SCHEMBL24413638

SCHEMBL24413638

O=C(Oc1ccc(Oc2cccc(I)c2)cc1)C(F)(F)S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.40
TNKS O95271 1/20 0.38
PARP15 Q460N3 1/20 0.38
PARP14 Q460N5 1/20 0.38
PARP10 Q53GL7 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
AKR1C3 P42330 1/20 0.38
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
CYP2C9 P11712 1/20 0.37
RAB9A P51151 1/20 0.37
TBXA2R P21731 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
KAT6A Q92794 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TLR8 Q9NR97 1/20 0.34
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
AR P10275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24413533 0.86 ELANE (0.46) ELANEPOLBTBXA2RMMP2MMP9
SCHEMBL24413785 0.82 ELANE (0.39) ELANETBXA2RTLR8MMP2MMP9
SCHEMBL24414011 0.82 ELANE (0.41) ELANETLR8
SCHEMBL24413654 0.82 THRB (0.41) ELANEPOLBCYP2C9PGRAR
SCHEMBL24413720 0.80 PCNA (0.39) ELANEPOLBCYP2C9PGRAR
SCHEMBL24414033 0.80 ELANE (0.44) ELANECYP2C9TBXA2RTLR8NR3C1
SCHEMBL24413641 0.79 ELANE (0.47) ELANEMMP2MMP9MMP13MMP14
SCHEMBL24414015 0.79 ELANE (0.37) ELANETBXA2RKDM4EPGRAR
SCHEMBL2605930 0.78 L3MBTL1 (0.43) ELANE
SCHEMBL24413615 0.77 ELANE (0.38) ELANECYP2C9TBXA2RARMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, FGFR1, NHERF1 ELANE 1517/4885TNKS 4798/4885PARP15 4549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.