SCHEMBL24413639

SCHEMBL24413639

Cc1cccc(I)c1Oc1ccc(OC(=O)C(F)(F)S(=O)(=O)O)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.37
FFAR1 O14842 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
AR P10275 1/20 0.33
LPAR1 Q92633 2/20 0.33
LPAR5 Q9H1C0 2/20 0.33
ATM Q13315 1/20 0.32
LIPE Q05469 1/20 0.31
TLR8 Q9NR97 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PRTN3 P24158 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24414014 0.84 ELANE (0.36) ELANE
SCHEMBL24414008 0.80 ELANE (0.39) ELANE
SCHEMBL24413720 0.80 PCNA (0.39) ELANEARHPGDHSD17B10SMN1; SMN2
SCHEMBL24413636 0.80 LPAR1 (0.43) ELANEFFAR1L3MBTL1ARLPAR1
SCHEMBL24413648 0.78 ELANE (0.40) ELANETLR8ALDH1A1HSD17B10
SCHEMBL24413533 0.77 ELANE (0.46) ELANEL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL24414033 0.77 ELANE (0.44) ELANETLR8ALDH1A1HSD17B10
SCHEMBL24413637 0.76 HSD17B10 (0.44) ELANEL3MBTL1ALDH1A1HPGDHSD17B10
SCHEMBL24413518 0.76 LMNA (0.35) ELANELIPESMN1; SMN2
SCHEMBL24413638 0.76 ELANE (0.40) ELANEARTLR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, FGFR1, NHERF1 ELANE 1517/4885FFAR1 33/4885L3MBTL1 2746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.