SCHEMBL24417501

SCHEMBL24417501

C=C/C=C\C=C(/C)c1nc(-c2ccccc2)nc(-c2ccc(-n3c4c(C)cc(C)cc4c4cc(C)cc(C)c43)cc2)n1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.34
KDM4E B2RXH2 2/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MTOR P42345 1/20 0.31
BLK P51451 1/20 0.31
BMX P51813 1/20 0.31
JAK3 P52333 1/20 0.31
BTK Q06187 1/20 0.31
AVPR1A P37288 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30646340 0.82 L3MBTL1 (0.43) RXRAKDM4ELMNAMAPTTSHR
SCHEMBL21291465 0.82 L3MBTL1 (0.43) RXRAKDM4ELMNAMAPTTSHR
SCHEMBL22083481 0.79 L3MBTL1 (0.42) KDM4ELMNAMAPTTSHRMAPK1
SCHEMBL23265814 0.78 KDM4E (0.35) RXRAKDM4ELMNAMAPTTSHR
SCHEMBL26051491 0.76 PTGER4 (0.35) RXRAKDM4EAVPR1A
SCHEMBL24677417 0.76 PTGER4 (0.32) RXRAKDM4E
SCHEMBL22905607 0.76 MEN1 (0.45) RXRAKDM4ELMNAMAPTMAPK1
SCHEMBL25527474 0.76 PTGS2 (0.35) KDM4ELMNAMAPTTSHRMAPK1
SCHEMBL19074874 0.76 LMNA (0.37) RXRAKDM4ELMNAMAPTTSHR
SCHEMBL23277705 0.76 PTGER4 (0.33) RXRAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220149281-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY PANEL AND DISPLAY DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2022-05-12 US disclosed