Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30825976 | 0.81 | MAPT (0.49) | MAPTHTR3AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27261502 | 0.81 | MAPT (0.49) | MAPTHTR3AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2447732 | 0.80 | DPP4 (0.39) | MAPTCHRNB2CHRNA4HSD11B1HTR3A | |
| SCHEMBL24540313 | 0.80 | DHFR (0.42) | MAPTCHRNB2CHRNA4HSD11B1HTR3A | |
| SCHEMBL30477815 | 0.80 | GCK (0.45) | MAPTCHRNB2CHRNA4HSD11B1HTR3A | |
| SCHEMBL17108483 | 0.80 | GCK (0.45) | MAPTCHRNB2CHRNA4HSD11B1HTR3A | |
| SCHEMBL4696975 | 0.77 | MAPT (0.67) | MAPTCHRNB2CHRNA4HSD11B1POLB | |
| SCHEMBL24421700 | 0.77 | ALDH1A1 (0.56) | MAPTKDM4EALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL18641228 | 0.76 | AR (0.43) | MAPTGPR119KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1766217 | 0.76 | ENPP2 (0.38) | MAPTCHRNB2CHRNA4HSD11B1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144838-A1 | Compounds as Inhibitors of Macrophage Migration Inhibitory Factor | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144838-A1 | Compounds as Inhibitors of Macrophage Migration Inhibitory Factor | MIF, MMP12, SLC11A2 | MAPT 4347/4885CHRNB2 4066/4885CHRNA4 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.