Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381147 | 0.83 | ACHE (0.61) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL31225036 | 0.83 | CYP1A2 (0.58) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL4203451 | 0.81 | HSD11B1 (0.59) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL27546595 | 0.81 | LOXL2 (0.72) | ALDH1A1MAPTMEN1KMT2ALOXL2 | |
| SCHEMBL10915895 | 0.80 | POLB (0.58) | ALDH1A1MAPTKDM4EUSP2LMNA | |
| SCHEMBL6554976 | 0.80 | MEN1 (0.44) | ALDH1A1MAPTKDM4EUSP2LMNA | |
| SCHEMBL254528 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EUSP2LMNA | |
| SCHEMBL14598173 | 0.79 | MAPT (0.56) | ALDH1A1MAPTKCNH2DRD3DRD2 | |
| SCHEMBL10180212 | 0.79 | TSHR (0.57) | MAPTKCNH2DRD3DRD2SMN1; SMN2 | |
| SCHEMBL20380076 | 0.79 | HTT (0.64) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774755-B1 | SPIROCYCLIC COMPOUNDS AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | PHENEX DISCOVERY VERWALTUNGS GMBH (DE) | 2022-05-18 | — | — | EP | disclosed |