Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380076 | 0.95 | HTT (0.64) | HSD11B1HTTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL27546595 | 0.86 | LOXL2 (0.72) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL3381147 | 0.85 | ACHE (0.61) | ALDH1A1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL31225036 | 0.85 | CYP1A2 (0.58) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL31273875 | 0.84 | TSHR (0.67) | HSD11B1MAPTMEN1KMT2ATSHR | |
| SCHEMBL19332554 | 0.84 | CYP2C19 (0.50) | HSD11B1HTTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6512769 | 0.83 | HSD11B1 (0.56) | HSD11B1HTTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL30963225 | 0.82 | HTT (0.66) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL13723216 | 0.82 | CYP1A2 (0.57) | HTTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL30963204 | 0.82 | ALDH1A1 (0.50) | HSD11B1HTTALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252841-B2 | Methods of inhibiting bacterial virulence and compounds relating thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-08-28 | — | — | US | disclosed |
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2009-01-08 | — | — | US | disclosed |
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2009-01-08 | — | — | US | disclosed |
| WO-2008157216-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | WYETH (US) | 2008-12-24 | — | — | WO | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| EP-0050225-A1 | Sulfones, their preparation and use | BASF Aktiengesellschaft (DE) | 1982-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012308-A1 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES | HTR6, HTR2B, HTR3B | HSD11B1 1945/4885HTT 285/4885ALDH1A1 721/4885 |
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | HSD11B1 678/4885HTT 2299/4885ALDH1A1 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.