Sugi Predict

Sugi Predict / Compounds / SCHEMBL24433581

SCHEMBL24433581

SCHEMBL24433581

CC(C)N(c1ccccc1-c1cccc2ccccc12)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.40
▸ PTPN1 P18031 1/20 0.38
▸ SIGMAR1 Q99720 1/20 0.38
▸ AKR1C3 P42330 1/20 0.36
▸ AKR1C2 P52895 1/20 0.36
▸ NPC1 O15118 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ PPARG P37231 5/20 0.35
▸ PPARA Q07869 5/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ PPARD Q03181 1/20 0.35
▸ DNMT1 P26358 1/20 0.34
▸ NISCH Q9Y2I1 1/20 0.34
▸ HTR1A P08908 2/20 0.34
▸ HTR7 P34969 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ SLC22A12 Q96S37 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24433663 0.79 ALOX5 (0.37) ALOX5PTPN1AKR1C3AKR1C2NPC1
SCHEMBL13338497 0.77 SIGMAR1 (0.43) ALOX5PTPN1SIGMAR1AKR1C3AKR1C2
SCHEMBL13338423 0.74 AKR1C3 (0.42) ALOX5PTPN1SIGMAR1AKR1C3AKR1C2
SCHEMBL13338562 0.74 SIGMAR1 (0.39) ALOX5PTPN1SIGMAR1AKR1C3AKR1C2
SCHEMBL5223360 0.73 SIGMAR1 (0.50) ALOX5SIGMAR1MAPTCYP2C19NISCH
SCHEMBL29177776 0.73 SIGMAR1 (0.44) ALOX5PTPN1SIGMAR1NPC1MAPT
SCHEMBL13338539 0.71 MAOA (0.38) ALOX5PTPN1SIGMAR1AKR1C3AKR1C2
SCHEMBL13338661 0.71 AKR1C3 (0.39) ALOX5PTPN1SIGMAR1AKR1C3AKR1C2
SCHEMBL24433767 0.70 ADRB2 (0.38) NPC1MAPTRAB9ASMN1; SMN2KDM4E
SCHEMBL13338595 0.70 AKR1C3 (0.39) ALOX5PTPN1SIGMAR1AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 — — US disclosed
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 — — US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, LBR, C1R ALOX5 1710/4885PTPN1 3922/4885SIGMAR1 104/4885
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND3 ALOX5 784/4885PTPN1 4652/4885SIGMAR1 1522/4885
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ODC1, OCIAD1, OCIAD2 ALOX5 428/4885PTPN1 4819/4885SIGMAR1 845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.