SCHEMBL24433703

SCHEMBL24433703

CNC(=N)NC(=N)NCc1coc(C)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4856944 0.84 L3MBTL1 (0.32) L3MBTL1
SCHEMBL14868592 0.82 L3MBTL1 (0.33) L3MBTL1
SCHEMBL18624786 0.73 LMNA (0.46)
SCHEMBL14868581 0.73 ALDH1A1 (0.39)
SCHEMBL24433739 0.73 LMNA (0.32)
SCHEMBL24433704 0.72 TSHR (0.34)
SCHEMBL14868321 0.71 ALOX12 (0.47) L3MBTL1
Hydrochloric Acid SCHEMBL2246639 0.70 MAPT (0.48) L3MBTL1
Hydrochloric Acid SCHEMBL17186315 0.70 MAPT (0.48) L3MBTL1
SCHEMBL14868418 0.70 ERCC1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220151957-A1 BIGUANIDE COMPOSITIONS AND METHODS OF TREATING METABOLIC DISORDERS ANJI PHARMACEUTICALS INC. 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220151957-A1 BIGUANIDE COMPOSITIONS AND METHODS OF TREATING METABOLIC DISORDERS SLC5A2, SLC5A1, GPR119 L3MBTL1 4566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.