Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26947621 | 0.78 | OPRM1 (0.44) | OPRM1OPRL1CHRM4CHRM2CHRM5 | |
| SCHEMBL10270829 | 0.76 | HSD11B1 (0.38) | OPRM1OPRL1CHRM4CHRM2CHRM5 | |
| SCHEMBL10270572 | 0.76 | HSD11B1 (0.38) | OPRM1OPRL1CHRM4CHRM2CHRM5 | |
| SCHEMBL29791494 | 0.74 | GRIN1 (0.46) | OPRM1OPRL1CHRM4CHRM2CHRM5 | |
| SCHEMBL2583270 | 0.73 | CHRM2 (0.38) | OPRM1OPRL1CHRM4CHRM2CHRM5 | |
| SCHEMBL16693929 | 0.73 | CHRM2 (0.38) | OPRM1OPRL1CHRM4CHRM2CHRM5 | |
| SCHEMBL21513708 | 0.71 | SLC6A2 (0.41) | OPRM1OPRL1CHRM4SLC6A2SLC6A4 | |
| SCHEMBL29969746 | 0.71 | SLC6A2 (0.41) | OPRM1OPRL1CHRM4SLC6A2SLC6A4 | |
| SCHEMBL29730766 | 0.71 | GRIN1 (0.51) | OPRM1OPRL1CHRM4CHRM2CHRM5 | |
| SCHEMBL13447345 | 0.69 | GRIN1 (0.54) | OPRM1OPRL1CHRM4CHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | OPRM1 4412/4885OPRL1 3554/4885CHRM4 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.