Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31252817 | 0.85 | ESRRG (0.48) | CES2P2RX1KIF11ALDH1A1CYP3A4 | |
| SCHEMBL323569 | 0.85 | ESRRG (0.48) | CES2P2RX1KIF11ALDH1A1CYP3A4 | |
| SCHEMBL27952265 | 0.82 | LMNA (0.46) | CES2ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL9835183 | 0.82 | ALDH1A1 (0.50) | CES2ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL24895058 | 0.82 | CA12 (0.55) | CES2P2RX1KIF11MGLLALDH1A1 | |
| SCHEMBL31004884 | 0.81 | CES2 (0.72) | CES2KIF11ALDH1A1HPGDMAPT | |
| SCHEMBL4761587 | 0.81 | KIF11 (0.47) | CES2P2RX1KIF11GAAKMT2A | |
| SCHEMBL18354210 | 0.81 | CES2 (0.47) | CES2P2RX1KIF11ALDH1A1GAA | |
| SCHEMBL2001145 | 0.81 | CES2 (0.72) | CES2KIF11ALDH1A1HPGDMAPT | |
| SCHEMBL24436898 | 0.80 | CA12 (0.61) | CES2P2RX1GAAKDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220157484-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-05-19 | — | — | US | disclosed |