Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 7/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.47 |
| ▸ | ABAT | P80404 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30203126 | 0.86 | APP (0.63) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL856737 | 0.86 | APP (0.63) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL1414751 | 0.83 | ALDH1A1 (0.54) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL4130397 | 0.83 | ALDH1A1 (0.63) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL20869201 | 0.82 | ALDH1A1 (0.66) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL584601 | 0.80 | EPHX2 (0.50) | ALDH1A1AOX1APPALDH5A1ABAT | |
| SCHEMBL7255672 | 0.79 | ALDH1A1 (0.46) | ALDH1A1AOX1RAB9ATDP1 | |
| SCHEMBL15664456 | 0.79 | ALDH1A1 (0.43) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL7857195 | 0.79 | ALDH1A1 (0.43) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL670456 | 0.79 | ALDH1A1 (0.43) | ALDH1A1AOX1KDM4EPTGS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| EP-4001336-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | ALDH1A1 1490/4885AOX1 529/4885KDM4E 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.