Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.42 |
| ▸ | ABAT | P80404 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445666 | 0.83 | ALDH1A1 (0.61) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL1414779 | 0.80 | ALDH1A1 (0.62) | ALDH1A1AOX1KDM4ERAB9ATTR | |
| SCHEMBL4130397 | 0.78 | ALDH1A1 (0.63) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL17051274 | 0.77 | ALDH1A1 (0.61) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL20869201 | 0.77 | ALDH1A1 (0.66) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL1414586 | 0.77 | ALDH5A1 (0.48) | ALDH1A1TTRALDH5A1ABATHPGD | |
| SCHEMBL1414753 | 0.76 | ALDH1A1 (0.56) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL2254768 | 0.74 | ALDH1A1 (0.57) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL15952417 | 0.73 | ALDH1A1 (0.56) | ALDH1A1AOX1KDM4EPTGS2RAB9A | |
| SCHEMBL1414595 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025661-B1 | FLUOROALKYLOXY-CONTAINING COMBRETASTATIN DERIVATIVES, PREPARATION AND USE THEREOF | ZHEJIANG DADE PHARMACEUTICAL GROUP CO LTD (CN) | 2011-03-16 | — | — | EP | disclosed |
| US-7786098-B2 | Fluoroalkoxycombretastatin derivatives, method for producing the same and use thereof | ZHEJIANG DADE PHARMACEUTICAL GROUP CO. LTD. (CN) | 2010-08-31 | — | — | US | disclosed |
| EP-2025661-A1 | FLUOROALKYLOXY-CONTAINING COMBRETASTATIN DERIVATIVES, PREPARATION AND USE THEREOF | Zhejiang Dade Pharmaceutical Group Co., Ltd. (CN) | 2009-02-18 | — | — | EP | disclosed |
| US-20080306027-A1 | Fluoroalkoxycombretastatin Derivatives, Method For Producing the Same and Use Thereof | ZHEJIANG DADE PHARMACEUTICAL GROUP CO., LTD. (CN) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306027-A1 | Fluoroalkoxycombretastatin Derivatives, Method For Producing the Same and Use Thereof | TUBB, TUBB1, TUBB3 | ALDH1A1 4116/4885AOX1 3559/4885KDM4E 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.