SCHEMBL1024889

SCHEMBL1024889

Nc1cc(OC(F)(F)F)ccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
MAPT P10636 5/20 0.55
GAA P10253 4/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
KDM4E B2RXH2 3/20 0.55
BLM P54132 2/20 0.55
RECQL P46063 2/20 0.55
THRB P10828 1/20 0.55
MCL1 Q07820 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
GPR3 P46089 3/20 0.44
ALOX15 P16050 4/20 0.44
HSD17B10 Q99714 4/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
PKM P14618 2/20 0.44
USP2 O75604 2/20 0.44
LMNA P02545 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31286071 1.00 ALDH1A1 (0.55) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL6938751 0.85 ALDH1A1 (0.52) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL30623356 0.85 ALDH1A1 (0.52) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL6756103 0.84 CYP3A4 (0.45) MAPTGAASMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL6756046 0.82 RAB9A (0.45) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL24445841 0.81 GPR3 (0.48) MAPTGAASMN1; SMN2MEN1KMT2A
SCHEMBL442684 0.81 NR4A1 (0.56) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL29546263 0.81 NR4A1 (0.56) ALDH1A1MAPTGAASMN1; SMN2MEN1
SCHEMBL4615608 0.80 ALDH1A1 (0.60) ALDH1A1MAPTGAASMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL9526864 0.79 NR4A1 (0.54) ALDH1A1MAPTGAASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
US-12398097-B2 WDR5-MYC inhibitors VANDERBILT UNIVERSITY (US) 2025-08-26 US disclosed
US-11981686-B2 Urea compound having substituent DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-05-14 US disclosed
US-20230058950-A1 UREA COMPOUND HAVING SUBSTITUENT DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-02-23 US disclosed
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO. LTD. (JP) 2023-02-16 US disclosed
EP-4067343-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2022-10-05 EP disclosed
US-20220289673-A1 WDR5-MYC INHIBITORS VANDERBILT UNIVERSITY 2022-09-15 US disclosed
EP-3915558-A1 SUBSTITUENT-INCLUDING UREA COMPOUND Daiichi Sankyo Company, Limited (JP) 2021-12-01 EP disclosed
EP-3421466-B1 BENZOXAZOLE COMPOUND OR SALT THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME NIHON NOHYAKU CO LTD (JP) 2021-10-27 EP disclosed
CN-113382767-A Substituted urea compounds 第一三共株式会社 2021-09-10 CN disclosed
CN-1520298-A Pyrazolopyrimidines as therapeutic agents �����ʩ���عɷݹ�˾ 2004-08-11 CN disclosed
EP-1385524-A1 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS Abbott GmbH & Co. KG (DE) 2004-02-04 EP disclosed
EP-1379528-A1 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS ABBOTT GmbH (DE) 2004-01-14 EP disclosed
US-20040006083-A1 Pyrazolopyrimidines as therapeutic agents ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2004-01-08 US disclosed
US-20030109714-A1 Transition metal mediated process ABBOTT GMBH & CO. KG (DE) 2003-06-12 US disclosed
US-20030009034-A1 Transition metal mediated process ABBOTT GMBH & CO. KG (DE) 2003-01-09 US disclosed
US-20020156081-A1 Pyrazolopyrimidines as therapeutic agents ABBOTT LABORATORIES (US) 2002-10-24 US disclosed
WO-2002080926-A1 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS ABBOTT GMBH & CO. KG (DE) 2002-10-17 WO disclosed
WO-2002076986-A1 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS ABBOTT GMBH & CO. KG (DE) 2002-10-03 WO disclosed
WO-2002076960-A1 TRANSITION METAL MEDIATED PROCESS ABBOTT GMBH & CO. KG (DE) 2002-10-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981686-B2 Urea compound having substituent SIRT6, SIRT1, SIRT2 ALDH1A1 618/4885MAPT 1249/4885GAA 3552/4885
US-20040006083-A1 Pyrazolopyrimidines as therapeutic agents DPYD, UGT1A1, ABCB1 ALDH1A1 81/4885MAPT 3448/4885GAA 678/4885
US-20220289673-A1 WDR5-MYC INHIBITORS MYC, WDR5, MYCBP ALDH1A1 3953/4885MAPT 1222/4885GAA 3730/4885
US-20230058950-A1 UREA COMPOUND HAVING SUBSTITUENT SIRT6, SIRT1, SIRT2 ALDH1A1 618/4885MAPT 1249/4885GAA 3552/4885
US-20030009034-A1 Transition metal mediated process TPMT, ABAT, TFAM ALDH1A1 1136/4885MAPT 675/4885GAA 849/4885
US-20030109714-A1 Transition metal mediated process TPMT, ABAT, TFAM ALDH1A1 1136/4885MAPT 675/4885GAA 849/4885
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB ALDH1A1 287/4885MAPT 3207/4885GAA 2659/4885
US-12398097-B2 WDR5-MYC inhibitors MYC, WDR5, MYCBP ALDH1A1 3953/4885MAPT 1222/4885GAA 3730/4885
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF MYB, MLX, EP300 ALDH1A1 235/4885MAPT 3490/4885GAA 3048/4885
US-20020156081-A1 Pyrazolopyrimidines as therapeutic agents DPYD, CYP2D6, UGT1A1 ALDH1A1 99/4885MAPT 3263/4885GAA 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.