Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24455989 | 1.00 | L3MBTL1 (0.38) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL24456633 | 1.00 | L3MBTL1 (0.38) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL24456521 | 1.00 | L3MBTL1 (0.38) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL24456371 | 1.00 | L3MBTL1 (0.38) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL1458970 | 0.95 | PIK3CA (0.38) | L3MBTL1SMN1; SMN2ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL24456135 | 0.81 | ALDH1A1 (0.33) | L3MBTL1SMN1; SMN2ALDH1A1MAPTPIK3CD | |
| SCHEMBL9936717 | 0.80 | GABRP (0.42) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL20870267 | 0.78 | UHRF1 (0.47) | LMNAPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL1459785 | 0.75 | GABRA1 (0.39) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL16783037 | 0.75 | HTR7 (0.47) | MAPTKDM4ECYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109492-A1 | PYRROLOPYRIDAZINE COMPOUNDS AS KINASE INHIBITORS | GOSSAMER BIOSERVICES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |