SCHEMBL24460222

SCHEMBL24460222

Cc1ccc(O)c2c(CCN(C)C(C)C)c[nH]c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR1A P08908 5/20 0.54
▸ HTR2A P28223 12/20 0.50
▸ HTR2C P28335 9/20 0.48
▸ HTR2B P41595 9/20 0.48
▸ HTR1D P28221 2/20 0.44
▸ HTR1B P28222 2/20 0.44
▸ HTR1E P28566 2/20 0.44
▸ HTR7 P34969 2/20 0.44
▸ HTR5A P47898 2/20 0.44
▸ HTR6 P50406 2/20 0.44
▸ DRD1 P21728 1/20 0.44
▸ ADORA2A P29274 1/20 0.44
▸ ADORA2B P29275 1/20 0.44
▸ DRD3 P35462 1/20 0.44
▸ HTR3E A5X5Y0 1/20 0.33
▸ HTR3B O95264 1/20 0.33
▸ HTR1F P30939 1/20 0.33
▸ HTR3A P46098 1/20 0.33
▸ HTR4 Q13639 1/20 0.33
▸ HTR3D Q70Z44 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25240749 0.88 HTR1A (0.52) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL25029851 0.86 HTR1A (0.72) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL25008690 0.85 HTR1A (0.50) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL25029867 0.83 HTR1A (0.57) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL31077923 0.82 HTR1A (0.56) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL25288798 0.82 HTR1A (0.56) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL25024712 0.82 HTR1A (0.50) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL24460448 0.82 HTR1A (0.50) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL24460460 0.82 HTR1A (0.50) HTR1AHTR2AHTR2CHTR2BHTR1D
SCHEMBL25748357 0.82 HTR6 (0.46) HTR1AHTR2AHTR2CHTR2BHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101038-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-03-27 — — US disclosed
US-20250059217-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF BRIGHT MINDS BIOSCIENCES INC. (CA) 2025-02-20 — — US disclosed
EP-4452937-A1 COMPOUNDS Psylo Pty Ltd (AU) 2024-10-30 — — EP disclosed
CN-118715204-A Compounds of formula (I) 普赛洛私人有限公司 2024-09-27 — — CN disclosed
CN-117897376-A Heterocyclic compounds and process for preparing same 光明智慧生物科学公司 2024-04-16 — — CN disclosed
EP-4347561-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF Bright Minds Biosciences Inc. (CA) 2024-04-10 — — EP disclosed
WO-2023115166-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2023115166-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed
US-20230051548-A1 NITRILATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2023-02-16 — — US disclosed
WO-2022246554-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF BRIGHT MINDS BIOSCIENCES INC. (CA) 2022-12-01 — — WO disclosed
WO-2022104475-A1 NITRILATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2022-05-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101038-A1 COMPOUNDS NLN, SLC18A2, PYGB HTR1A 185/4885HTR2A 94/4885HTR2C 23/4885
US-20230051548-A1 NITRILATED PSILOCYBIN DERIVATIVES AND METHODS OF USING PNMT, HTR1B, HTR2B HTR1A 36/4885HTR2A 34/4885HTR2C 8/4885
US-20250059217-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF PREPARATION THEREOF OPRL1, OPRK1, CNR2 HTR1A 306/4885HTR2A 413/4885HTR2C 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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