Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460951 | 0.83 | ALDH1A1 (0.48) | CNR2ROCK2DRD2DRD1DRD4 | |
| SCHEMBL24460737 | 0.83 | ALDH1A1 (0.48) | CNR2ROCK2DRD2DRD1DRD4 | |
| SCHEMBL24460679 | 0.80 | DRD4 (0.52) | CNR2ROCK2DRD2DRD1DRD4 | |
| SCHEMBL24460661 | 0.74 | KDM4E (0.56) | CNR2POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL24460625 | 0.74 | KDM4E (0.56) | CNR2POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL24460749 | 0.73 | CNR2 (0.70) | CNR2DRD2DRD1DRD4DRD5 | |
| SCHEMBL24460758 | 0.71 | ALDH1A1 (0.59) | CNR2ROCK2DRD2DRD1DRD4 | |
| SCHEMBL24460730 | 0.70 | CNR2 (0.52) | CNR2DRD2DRD1DRD4DRD5 | |
| SCHEMBL24460624 | 0.70 | GAA (0.58) | CNR2DRD2DRD1DRD4DRD5 | |
| SCHEMBL24460628 | 0.69 | ALDH1A1 (0.52) | CNR2DRD4POLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |