Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 8/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460625 | 0.75 | KDM4E (0.56) | PDE2ACNR2CCR2MEN1GAA | |
| SCHEMBL24460661 | 0.75 | KDM4E (0.56) | PDE2ACNR2CCR2MEN1GAA | |
| SCHEMBL24460692 | 0.72 | PDE2A (0.52) | PDE2ACNR2DRD4 | |
| SCHEMBL24460956 | 0.72 | CNR2 (0.53) | PDE2ACNR2DRD4MEN1KMT2A | |
| SCHEMBL24460697 | 0.72 | PDE2A (0.52) | PDE2ACNR2DRD4 | |
| SCHEMBL24460730 | 0.71 | CNR2 (0.52) | PDE2ACNR2DRD4CCR2MEN1 | |
| SCHEMBL21619965 | 0.71 | NOTUM (0.46) | PROKR1GAA | |
| SCHEMBL24460749 | 0.71 | CNR2 (0.70) | PDE2ACNR2DRD4MEN1KMT2A | |
| SCHEMBL24460628 | 0.70 | ALDH1A1 (0.52) | PDE2ACNR2DRD4 | |
| SCHEMBL12950818 | 0.69 | DRD2 (0.55) | PROKR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |