Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968253 | 0.79 | MAPT (0.54) | MTORIDO1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL7979826 | 0.72 | LMNA (0.53) | IDO1LMNAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL255088 | 0.72 | MTOR (1.00) | MTORMAOBMEN1KMT2ANPC1 | |
| SCHEMBL7785354 | 0.68 | IDO1 (0.53) | MAOBIDO1ALDH1A1NPSR1KMT2A | |
| SCHEMBL4317540 | 0.68 | MEN1 (0.49) | IDO1LMNAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL30753398 | 0.68 | MEN1 (0.60) | IDO1HPGDALDH1A1NPSR1MEN1 | |
| SCHEMBL173527 | 0.68 | MEN1 (0.60) | IDO1HPGDALDH1A1NPSR1MEN1 | |
| SCHEMBL10220026 | 0.67 | MTOR (0.80) | MTORMAOBLMNAALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL4425282 | 0.67 | LMNA (0.48) | IDO1LMNAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL12337052 | 0.67 | MAPT (0.58) | IDO1LMNAALDH1A1L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002350-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2024-01-04 | — | — | US | claimed |
| WO-2022108980-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-05-27 | — | — | WO | claimed |
| US-20240002350-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2024-01-04 | — | — | US | disclosed |
| WO-2022108980-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022108980-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002350-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | PEBP1, ALOX15, ALOX15B | MTOR 2005/4885MAOB 1222/4885IDO1 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.