SCHEMBL24465376

SCHEMBL24465376

NN(C(=O)c1cccc(C2CO2)c1)S(=O)(=O)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.55
KDM1A O60341 2/20 0.35
MAOB P27338 2/20 0.35
MAOA P21397 1/20 0.35
GSTO1 P78417 3/20 0.35
TSHR P16473 1/20 0.33
KMO O15229 1/20 0.31
KLK1 P06870 1/20 0.31
KLK5 Q9Y337 1/20 0.31
MLYCD O95822 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24465368 0.84 PARP1 (0.36) PARP1GSTO1TSHR
SCHEMBL8042370 0.75 CES1 (0.42) PARP1TSHRMLYCD
SCHEMBL24465375 0.73 OPRM1 (0.36)
SCHEMBL30004753 0.72 PARP1 (1.00) PARP1KDM1AMAOBMAOATSHR
SCHEMBL4274420 0.70 PARP1 (0.72) PARP1TSHRKMO
SCHEMBL24465320 0.69 OPRM1 (0.33)
SCHEMBL1499340 0.69 PARP1 (0.70) PARP1TSHRKMO
SCHEMBL24465300 0.69 ALDH1A1 (0.41) PARP1TSHR
SCHEMBL24452782 0.67 PARP1 (0.47) PARP1GSTO1
Aniline SCHEMBL28655458 0.66 PARP1 (0.65) PARP1KDM1AMAOATSHRKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006921-A2 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE Shin-Etsu Chemical Co., Ltd. (JP) 2022-06-01 EP disclosed