SCHEMBL24465368

SCHEMBL24465368

NN(C(=O)c1ccc(C2CO2)cc1)S(=O)(=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.36
GSTO1 P78417 3/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24465376 0.84 PARP1 (0.55) PARP1GSTO1TSHR
SCHEMBL8042370 0.76 CES1 (0.42) PARP1TSHR
SCHEMBL24465384 0.71 RORC (0.32) GSTO1TSHR
SCHEMBL24465268 0.71 CA1 (0.33) GSTO1TSHR
SCHEMBL24465300 0.70 ALDH1A1 (0.41) PARP1TSHR
SCHEMBL4444258 0.66 TSHR (0.54) PARP1TSHR
SCHEMBL24465338 0.65 DHFR (0.43)
SCHEMBL12385477 0.65 TSHR (0.46) PARP1GSTO1TSHR
SCHEMBL2619374 0.65 LMNA (0.49) PARP1TSHR
SCHEMBL24465375 0.64 OPRM1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006921-A2 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE Shin-Etsu Chemical Co., Ltd. (JP) 2022-06-01 EP disclosed