Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870700 | 0.77 | MLYCD (0.48) | CES1HSD11B1MLYCDNR1H3NR1H2 | |
| SCHEMBL27489012 | 0.77 | HSD11B1 (0.47) | CES1HSD11B1POLBTSHRTDP1 | |
| SCHEMBL974470 | 0.77 | HSD11B1 (0.47) | CES1HSD11B1POLBTSHRTDP1 | |
| SCHEMBL24465368 | 0.76 | PARP1 (0.36) | TSHRPARP1 | |
| SCHEMBL28730355 | 0.76 | HSD11B1 (0.50) | CES1HSD11B1POLBTSHRTDP1 | |
| SCHEMBL24465376 | 0.75 | PARP1 (0.55) | MLYCDTSHRPARP1 | |
| SCHEMBL2481566 | 0.73 | CES1 (0.48) | CES1MLYCDNR1H3NR1H2POLB | |
| SCHEMBL24465375 | 0.73 | OPRM1 (0.36) | — | |
| SCHEMBL9026301 | 0.71 | HSD11B1 (0.46) | HSD11B1POLBTSHRTDP1L3MBTL1 | |
| SCHEMBL9956627 | 0.70 | CES1 (0.50) | CES1HSD11B1MLYCDNR1H3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001948-A1 | BISIMINO-SUBSTITUTED PHENYL COMPOUNDS AND THEIR USE AS PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-24 | — | — | EP | disclosed |
| EP-0988293-A1 | BISIMINO-SUBSTITUTED PHENYL COMPOUNDS AND THEIR USE AS PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-29 | — | — | EP | disclosed |
| WO-1999006379-A1 | BISIMINO-SUBSTITUTED PHENYL COMPOUNDS AND THEIR USE AS PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-11 | — | — | WO | disclosed |
| WO-1998056774-A1 | BISIMINO-SUBSTITUTED PHENYL COMPOUNDS AND THEIR USE AS PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-17 | — | — | WO | disclosed |