Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074957 | 0.79 | ALOX5 (0.37) | MAPTTP53MAPK1NISCHTSHR | |
| SCHEMBL9368915 | 0.75 | NISCH (0.31) | NISCH | |
| SCHEMBL28032947 | 0.74 | ADORA3 (0.42) | KDM4ECYP1A2NPC1RAB9AMAPT | |
| SCHEMBL3131316 | 0.74 | DRD2 (0.34) | KDM4ELMNAMAPTTP53TDP1 | |
| SCHEMBL31540166 | 0.73 | NISCH (0.44) | KDM4EALDH1A1NISCHCYP2C9CYP2C19 | |
| SCHEMBL9664108 | 0.73 | NISCH (0.31) | MAPTTP53MAPK1NISCHTSHR | |
| SCHEMBL2596889 | 0.72 | ALDH1A1 (0.32) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31069501 | 0.71 | NISCH (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL25430258 | 0.67 | ALDH1A1 (0.35) | KDM4ELMNAPOLBBLMNPC1 | |
| Dipyridyl SCHEMBL29351528 | 0.65 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119978223-A | Preparation method of polymer coating agent for drilling fluid | 濮阳市绿色奇点新材料有限公司 | 2025-05-13 | — | — | CN | claimed |
| EP-0698022-B1 | 1,4-BENZOXAZINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | ZENECA LTD (GB) | 1997-09-17 | — | — | EP | claimed |
| EP-0698022-A1 | 1,4-BENZOXAZINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | ZENECA LTD (GB) | 1996-02-28 | — | — | EP | claimed |
| WO-1994026739-A1 | 1,4-BENZOXAZINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | ZENECA LIMITED (GB) | 1994-11-24 | — | — | WO | claimed |
| CN-119978223-A | Preparation method of polymer coating agent for drilling fluid | 濮阳市绿色奇点新材料有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-119978223-A | Preparation method of polymer coating agent for drilling fluid | 濮阳市绿色奇点新材料有限公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-2627652-B1 | PYRIDYL BENZOXAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE THEREOF | DAE WOONG PHARMA (KR) | 2015-12-16 | — | — | EP | disclosed |
| CN-103153990-B | Novel pyridyl benzoxazine derivatives, pharmaceutical composition comprising the same, and use thereof | DAE WOONG PHARMA | 2015-06-17 | — | — | CN | disclosed |
| CN-103153990-B | Novel pyridyl benzoxazine derivatives, pharmaceutical composition comprising the same, and use thereof | DAE WOONG PHARMA | 2015-06-17 | — | — | CN | disclosed |
| EP-2627652-A2 | NOVEL PYRIDYL BENZOXAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE THEREOF | Daewoong Pharmaceutical Co., Ltd (KR) | 2013-08-21 | — | — | EP | disclosed |
| CN-103153990-A | Novel pyridyl benzoxazine derivatives, pharmaceutical composition comprising the same, and use thereof | DAE WOONG PHARMA | 2013-06-12 | — | — | CN | disclosed |
| CN-103153990-A | Novel pyridyl benzoxazine derivatives, pharmaceutical composition comprising the same, and use thereof | DAE WOONG PHARMA | 2013-06-12 | — | — | CN | disclosed |
| WO-2012050380-A2 | NOVEL PYRIDYL BENZOXAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2012-04-19 | — | — | WO | disclosed |
| US-8026235-B1 | Pyridyl benzoxazine derivatives, pharmaceutical composition comprising the same, and use thereof | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2011-09-27 | — | — | US | disclosed |
| JP-2002220389-A | PYRIDYLBENZOXAZINE DERIVATIVE, HERBICIDE AND ITS INTERMEDIATE | HOKKO CHEM IND CO LTD | 2002-08-09 | — | — | JP | disclosed |
| US-5700798-A | Methods for using benzoxazines for treating asthma | ZENECA LIMITED (GB) | 1997-12-23 | — | — | US | disclosed |
| EP-0698022-B1 | 1,4-BENZOXAZINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | ZENECA LTD (GB) | 1997-09-17 | — | — | EP | disclosed |
| EP-0698022-A1 | 1,4-BENZOXAZINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | ZENECA LTD (GB) | 1996-02-28 | — | — | EP | disclosed |
| US-5486515-A | 2-fluoroalkyl-1,4-benzoxaxines as potassium channel mediators | ZENECA LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |
| WO-1994026739-A1 | 1,4-BENZOXAZINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | ZENECA LIMITED (GB) | 1994-11-24 | — | — | WO | disclosed |